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高壮强

职位:助理教授

邮箱:zhuangqiang.gao@szu.edu.cn

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个人简介

高壮强,博士,2012年和2017年于福州大学分别获化学学士学位和分析化学博士学位;2016-2018年,在美国密歇根理工大学进行访问学者研究;2018-2019年,在美国中佛罗里达大学从事博士后研究;2019-2022年,在美国奥本大学继续开展博士后研究;2022年加入深圳大学生物医学工程学院。主要研究兴趣集中在功能纳米材料的可控合成与性质研究、高性能纳米生物传感方法的开发及疾病诊断应用。共发表SCI学术论文30余篇,累计他引2100余次,H-指数为23,其中(共同)第一作者及通讯作者论文16篇,包括ACS Nano 3篇,Nano Letters 1篇以及Analytical Chemistry 3篇。参与多个美国国家自然科学基金会(NSF)和国立卫生研究院(NIH)研究项目。受邀担任SCI期刊Biosensors和Chemosensors的特刊客座编辑以及Frontiers in Chemistry的评审编辑。

研究方向

生物传感、纳米材料、催化、局域表面等离激元、微流控、光学暗场成像、疾病诊断

代科研项目

(1) 美国国家自然科学基金会(National Science Foundation), Faculty Early Career Development Program (CAREER), CBET-1943302, CAREER: Nano-Plasmon Ruler Imaging for Direct Visualization of How Cells "Talk", 2020-06 至 2025-05, 50万美元, 在研, 参与;

(2) 美国国立卫生研究院会(National Institutes of Health), Maximizing Investigators' Research Award (MIRA) (R35), R35GM133795, Optofluidic Nanoplasmonic Biosensors for Next Generation Point-of-Care Immunoassays, 2019-09 至 2024-08, 190万美元, 在研, 参与;

(3) 美国国家自然科学基金会(National Science Foundation), 常规项目, DMR-2004546, A General and Robust Route to Highly Diverse Hollow Nanostructures with New Properties, 2020-06 至 2023-05, 47.5万美元, 在研, 参与;

(4) 美国国家自然科学基金会(National Science Foundation), Faculty Early Career Development Program (CAREER), CHE-1651307, CAREER: Engineering Bimetallic Nanostructures as Peroxidase Mimics for Diagnostic Applications, 2017-01 至 2022-01, 45.8万美元, 结题, 参与;

(5) 美国国家自然科学基金会(National Science Foundation), Rapid Response Research (RAPID), CBET-2027066, RAPID: Antibody-Based Nanoplasmonic Barcode Biosensors for COVID-19 Detection, 2020-05 至 2021-04, 20万美元, 结题, 参与。

代表性论文

(近五年,#co-first authors; *co-corresponding authors.):

(1) Yeyu Wang, Qiqi Yang, Zhuangqiang Gao,* Haifeng Dong,* Recent advance of RNA aptamers and DNAzymes for MicroRNA detection. Biosensors and Bioelectronics 2022, 212, 114423.

(2) Zhuangqiang Gao,* Chuanyu Wang, Jiacheng He, Pengyu Chen,*Pd@Ptnanodendrites as peroxidase nanomimics for enhanced colorimetric ELISA of cytokines with femtomolar sensitivity. Chemosensors 2022, 10, 359.

(3) Zhuangqiang Gao, Yujing Song, Te Yi Hsiao, Jiacheng He, Chuanyu Wang, Jialiang Shen, Siyuan Dai, Benjamin H. Singer, Katsuo Kurabayashi,* Pengyu Chen,* Machine-learning-assisted microfluidic nanoplasmonic digital immunoassay for cytokine storm profiling in COVID-19 patients. ACS Nano 2021, 15, 18023-18036.

(4) Zhuangqiang Gao, Shikuan Shao, Weiwei Gao, Dianyong Tang, Dianping Tang, Shengli Zou, Moon J. Kim, Xiaohu Xia,* Morphology-invariant metallic nanoparticles with tunable plasmonic properties. ACS Nano 2021, 15, 2428-2438.

(5) Zhuangqiang Gao, Haihang Ye, Qingxiao Wang, Moon J. Kim, Dianyong Tang, Zheng Xi, Zhiyuan Wei, Shikuan Shao, Xiaohu Xia,* Template regeneration in galvanic replacement: a route to highly diverse hollow nanostructures. ACS Nano 2020, 14, 791-801.

(6) Yang Wang,# Zhuangqiang Gao,# Bo Liu, Xiaohu Xia,* Peroxidase-AgAu hybrid nanocages as signal transducers for sensitive plasmonic colorimetric sensing. Journal of Materials Chemistry C 2019, 7, 15179-15187 (#equal contribution).

(7) Zhuangqiang Gao, Haihang Ye, Dianyong Tang, Jing Tao, Sanaz Habibi, Adrienne Minerick, Dianping Tang, Xiaohu Xia,* Platinum-decorated gold nanoparticles with dual functionalities for ultrasensitive colorimetric in vitro diagnostics. Nano Letters 2017, 17, 5572-5579.

(8) Zhuangqiang Gao, Grace G. Liu, Haihang Ye, Robert Rauschendorfer, Dianping Tang, Xiaohu Xia,* Facile colorimetric detection of silver ions with picomolar sensitivity. Analytical Chemistry 2017, 89, 3622-3629.