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助理教授

姓名:陈冕

职位:助理教授

邮箱:mian.chen@szu.edu.cn

      博士,助理教授,深圳市高层次人才C类。2014年获湖南大学分析化学博士学位。2014-2017年于深圳先进技术研究院从事博士后研究。2017年5月入职深圳大学生物医学工程学院。
 

 研究方向:纳米医学,包括基于功能化纳米材料的医学影像(光学、超声)、药物递送、声操控等研究。

 科研项目

(1)国家自然科学基金面上项目,81971637,磁纳米探针介导的肝癌靶向超声弹性成像研究,2020/01-2023/12, 55万,在研,主持
(2)国家自然科学基金青年科学基金项目,21505149,光声成像引导下肿瘤靶向治疗的金纳米探针的构建及应用研究,2016/01-2018/12,21万,结题,主持
(3)中国博士后基金,2015M582438,声操控金纳米探针用于药物靶向递送研究,2015/10-2016/12,5万元,结题,主持
(4)深圳市基础研究项目,JCYJ20170818141950351,多铁性纳米材料用于探针构建及肿瘤多模态分子影像研究,2018/03-2020/09, 50万,在研,主持
(5)湖南大学国家重点实验室开放基金,基于声操控的金纳米药物载体靶向递送研究,2015/1-2017/12,3万元,结题,主持
(6)深圳大学医学部青年拔尖计划,声场精准操控纳米粒子的理论与应用研究,2019/10-2021/10,10万元,在研,主持


 代表性论文

(1)1. Mian Chen, Feiyan Cai, Chen Wang, Zhiyong Wang, Long Meng, Fei Li, Pengfei Zhang, Xin Liu, Hairong Zheng*, Observation of metal nanoparticles for acoustic manipulation. Advanced Science, 2017, 4(5): 1600447.
(2)Wei Zhou#, Mian Chen#, Xiufang Liu, Wenjun Zhang, Feiyan Cai, Fei Li, Junru Wu, Jinping Wang, Yang Wang, Xiaowei Huang, Zhengrong Lin, Hui Zhou, Long Meng*, Lili Niu*, Hairong Zheng*, Selective photothermal ablation of cancer cells by patterned gold nanocages using surface acoustic waves. Lab on a Chip, 2019, 19(20): 3387-3396.
(3)Mian Chen#, Xiaoxiao He#, Kemin Wang*, Dinggeng He, Xiaohai Yang, Hui Shi, Inorganic fluorescent nanoprobes for cellular and subcellular imaging: status and challenges. Trends in Analytical Chemistry, 2014, 58, 120-129.
(4)Mian Chen#, Xiaoxiao He#, Kemin Wang*, Dinggeng He, Shuna Yang, Pengchao Qiu, Suye Chen, pH-responsive polymer/mesoporous silica nano-container through an acid cleavable linker for intracellular controlled release and tumor therapy in vivo. Journal of Materials Chemistry B, 2014, 2 (4), 428-436.
(5)Mian Chen#, Shuna Yang#, Xiaoxiao He*, Kemin Wang*, Pengchao Qiu, Dinggeng He, Co-loading of  coralyne and  indocyanine green into  adenine DNA- functionalized mesoporous  silica nanoparticles  for  pH- and  near-infrared- responsive chemothermal treatment of  cancer cells. Journal of Materials Chemistry B, 2014, 2(36): 6064-6071.
(6)Mian Chen#, Pengchao Qiu#, Xiaoxiao He*, Kemin Wang*, Suye Chen, Shuna Yang, Xiaosheng Ye, The adenine DNA self-assembly of pH-and near-infrared-responsive gold nanorod vehicles for the chemothermal treatment of cancer cells. Journal of Materials Chemistry B, 2014, 2(21): 3204-3213.
(7)Mian Chen#, Xiaoxiao He#, Bihua Shi, Kemin Wang*,Suye Chen, Bing Zhou, In vivo study of biodistribution and urinary excretion of silica nanoparticles with different size. Chinese Science Bulletin, 2013, 58: 568-574.
(8)Zhao, P., Wang, M., Chen, M., Chen, Z., Peng, X., Zhou, F., Song, J., & Qu, J. (2020). Programming cell pyroptosis with biomimetic nanoparticles for solid tumor immunotherapy. Biomaterials, 120142.
(9)Fei Li, Fei Yan, Zhiyi Chen, Junjun Lei, Jinsui Yu, Mian Chen, Wei Zhou, Long Meng, Lili Niu, Junru Wu, Jiangyu Li, Feiyan Cai*, Hairong Zheng*, Phononic crystal-enhanced near-boundary streaming for sonoporation. Applied Physics Letters, 2018, 113(8): 083701.
(10)Ming Dai, Xin Chen*, Tong Sun, Lingyao Yu, Mian Chen, Haoming Lin, Siping Chen*, A 2D magneto-acousto-electrical tomography method to detect conductivity variation using multifocus image method. Sensors, 2018, 18(7): 2373.


 专著

 

(1)Mian Chen#, Xiaoxiao He#, Kemin Wang*, Zhen Cheng*, Chapter 8. Nanoparticles in fluorescent optical imaging, 2013, 165-184. Book title: Nanotechnology in modern medical imaging and interventions. Editor: X. Yang. Nova Science Publisher. Inc.
(2)Hairong Zheng*, Yuanyi Zheng*, Fei Yan, Mian Chen, Pan Li, Next generation ultrasonic theranostic agents for molecular imaging and therapy: design, preparation and biomedical application, 2015, 153-188. Book title: Advances in Nanotheranostics II, Editors: Z. Dai. Springer Co.

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