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副教授

姓名:李自达

职位:副教授

邮箱:zidali@szu.edu.cn

课题组主页:https://zidalab.github.io
 

 研究方向:

(1)单分子核酸、免疫检测
(2)单细胞测序
(3)微工程化医学检验技术POCT

 

 工作经历:

 

(1)深圳大学生物医学工程学院,副教授,2024-至今
(2)深圳大学生物医学工程学院,助理教授,2018-2023
(3)香港大学机械工程系,研究助理,2012 - 2013

 科研项目:

 

(1)国家自然科学基金,青年项目,2024-2026,主持
(2)广东省自然科学基金,面上项目,2019-2022,主持
(3)广东省医学科学技术研究基金,青年项目,2019-2021,主持

 

 代表性论文 
#共同第一作者; *通讯作者
[1] Meichi Jin,# Jingyi Ding,# Yu Zhou, Jiazhao Chen, Yi Wang, and Zida Li* (2024). StratoLAMP: Label-free, multiplex digital loop-mediated isothermal amplification based on visual stratification of precipitate. Proceedings of the National Academy of Sciences, 121(2), e2314030121

[2] Linzhe Chen,# Jingyi Ding,# Hao Yuan, Chi Chen*, and Zida Li* (2022). deep-dLAMP: deep learning-enabled polydisperse emulsion-based digital loop-mediated isothermal amplification. Advanced Science, 9(9), 2105450

[3] Kai Wu,# Qi Fang,# Zhantao Zhao, and Zida Li* (2023). CoID-LAMP: Color-encoded, intelligent digital LAMP for multiplexed nucleic acid quantification. Analytical Chemistry, 95(11), 5069–5078

[4] Run Xie,# Yang Liu,# Xuyang Shi, Shiyu Wang, Zhantao Zhao, Longqi Liu, Ya Liu,* and Zida Li* (2023). Combinatorial perturbation sequencing on single cells using microwell-based droplet random pairing. Biosensors & Bioelectronics, 220, 114913

[5] Donghao Li,# Xinyu Liu,# Yujuan Chai,# Jieying Shan, Yihan Xie, Yong Liang, Susu Huang, Weidong Zheng, and Zida Li* (2022). Point-of-care blood coagulation assay enabled by printed circuit board-based digital microfluidics. Lab on a Chip, 22(4), 1473-0197

[6] Yi Zheng, Xufeng Xue, Yue Shao, Sicong Wang, Sajedeh Nasr Esfahani, Zida Li, Jonathon M. Muncie, Johnathon N. Lakins, Valerie M. Weaver, Deborah L. Gumucio, and Jianping Fu (2019). Controlled modeling of human epiblast and amnion development using stem cells. Nature, 573(7774), 421-425

[7] Yuanyuan Zheng#, Xufeng Xue#, Agnes M. Resto Irizarry, Zida Li, Yue Shao, Yi Zheng, Gang Zhao*, and Jianping Fu* (2019). A patterned model for neural tube development studies by human embryonic stem cells in a biomimetic niche. Science Advances, 5(12), eaax5993

 

 授权专利

 

[1] 李自达, 陈琳喆,郑卫东,单洁滢,谢以瀚,刘昕宇. 一种基于微流控技术的血液粘度检测装置及方法. 中国发明专利 ZL202110639057.6 (2023)
[2] 李自达, 赵展陶. 一种图像激发超微注射方法、系统及设备. 中国发明专利 ZL202211449260.8 (2023)
[3] 李自达, 方琪, 武凯. 基于深度学习的多重数字核酸检测方法、装置及相关介质. 中国发明专利ZL202211516857.X. (2023)
[4] 李自达, 余夏夏, 刘昕宇, 单洁滢, 谢以瀚. 体外诊断仿真系统及方法. 中国发明专利 ZL202110750662.0.  (2023)
[5] 李自达, 黄兰蛛, 郑卫东. 一种用于检测凝块收缩力的柔性微柱环阵列及其制备方法和应用. 中国发明专利 ZL202010260648.8. (2022)

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